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What is Tzield (teplizumab)?

About Tzield and why you have been prescribed it

What is Tzield?

In autoimmune Type 1 diabetes (T1D), the body’s immune system mistakenly attacks healthy cells in the pancreas called beta cells. Beta cells produce a hormone called insulin which helps your body convert sugar from your blood
into energy.1,2

Tzield helps to preserve the function of beta cells so that they can keep producing insulin. This may slow the progression from Stage 2 T1D to Stage 3 T1D.3

 

 

Who is it for?

Tzield is a medicine used to delay the start of Stage 3 T1D in adults and children aged 8 years and older who have Stage 2 T1D.4

Your doctor has prescribed you Tzield because there is evidence of Stage 2 T1D, which
is defined as having:3

Two or more T1D autoantibodies

Abnormal blood sugar levels

No evidence of Type 2 diabetes

You may be interested to find out…

What are autoantibodies?

Read more

How does Tzield work?

Read more

How is Tzield
given?

Read more

Tzield is a medicine used to delay the start of Stage 3 Type 1 diabetes. This condition happens when the body cannot make enough insulin on its own and may need insulin injections. This medicine is used in adults and children aged 8 years and older who have Stage 2 Type 1 diabetes.4

If you have any questions on how Tzield works or about your treatment with Tzield, ask your doctor.

This website is not intended to be a substitute for medical advice. Please refer to the Patient information leaflet and the Patient Guide for full safety information. You may have received these items from your doctor already.

 

References:

  1. Diabetes UK. What causes type 1 diabetes. Available at: https://www.diabetes.org.uk/about-diabetes/type-1-diabetes/causes. Accessed: November 2025.
  2. Diabetes UK. What is insulin? Available at: https://www.diabetes.org.uk/about-diabetes/looking-after-diabetes/treatments/insulin/what-is-insulin. Accessed: November 2025.
  3. TZIELD® (teplizumab) UK Summary of Product Characteristics. Accessed: November 2025.
  4. TZIELD® (teplizumab) UK Patient Information Leaflet. Accessed: November 2025.

© 2025 Sanofi. All rights reserved. MAT-XU-2501101 (V1.0) | November 2025