• You must not be given Tzield if you have had a severe allergic reaction to teplizumab or any of the other ingredients of this medicine
• Please refer to Section 6 of your Patient Information Leaflet  'Contents of the pack and other information' for the list of ingredients in the medicine.

Tell your doctor if you, or the person you care for, have any known allergies.

Before and after you are given Tzield, talk to your doctor or nurse about all your medical conditions, including if you:

• Have a serious infection – or an infection that does not go away or keeps coming back
• Are taking medicine that weakens your immune system (called immunosuppressive medication)
• Have recently had, or are planning to have, a vaccine. Tzield may affect how well a vaccine works
• Have any serious side effects described on this website or the Patient Information Leaflet 

Tell your doctor or nurse about the medicines you take, have recently taken, or plan to take, including:

• Prescription and non-prescription medicines, vitamins, and other supplements
• If you have had or are planning to have a vaccine. Tzield may affect how well a vaccine works. You should tell your doctor or nurse that you are being treated with Tzield before having a vaccine

Pregnancy
Tell your doctor or nurse if you are pregnant or plan to become pregnant. Tzield may harm your unborn baby.

• Do not have Tzield during pregnancy – and at least 30 days before a planned pregnancy

Breast-feeding
Tell your doctor or nurse if you are breast-feeding or plan to breast-feed. It is not known if Tzield passes into your breast milk and if it can harm your baby

• Talk to your doctor about the best way to feed your baby if you have Tzield
• If you are breast-feeding, it is best to pump and throw away your breast milk during treatment with Tzield – and for 20 days after treatment

Tzield is not expected to affect your ability to drive and use machines. However, if you feel tired, do not drive or use machines before discussing it with your doctor or nurse.